Cyclosporine A and tacrolimus reduce the amount of GLUT4 at the cell-surface in human adipocytes: increased endocytosis as a potential mechanism for the diabetogenic effects of immunosuppressive agents

Context:Immunosuppressive agentes are associated with profound metabolic side effects including new-onset diabetes and dyslipidemia after organ transplantation. Objective: Toi nvestigated the effects of the cyclosporine A(CsA)or tacrolimus ong lucose uptake and insulin signalling in human adipocytes...

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Bibliographic Details
Main Author: Pereira, Maria João (author)
Other Authors: Aureliano, M. (author), Palming, Jenny (author), Rizell, Magnus (author), Carvalho, Eugénia (author), Svensson, Maria K. (author), Eriksson, Jan W. (author)
Format: article
Language:eng
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10400.1/4856
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/4856