Rare double sex and mab-3-related transcription factor 1 regulatory variants in severe spermatogenic failure

The double sex and mab-3-related transcription factor 1 (DMRT1) gene has long been linked to sex-determining pathways across vertebrates and is known to play an essential role in gonadal development and maintenance of spermatogenesis in mice. In humans, the genomic region harboring the DMRT gene clu...

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Detalhes bibliográficos
Autor principal: Lima, A.C. (author)
Outros Autores: Carvalho, F. (author), Gonçalves, J. (author), Fernandes, S. (author), Marques, P.I. (author), Sousa, M. (author), Barros, A. (author), Seixas, A. (author), Amorim, A. (author), Conrad, D.F. (author), Lopes, M. (author)
Formato: article
Idioma:eng
Publicado em: 2016
Assuntos:
Doenças Genéticas
DMRT1
Male Infertility
Azoospermia
Spermatogenic Failure
Alternative Splicing
cis-regulatory Variants
Double Sex and mab-3-related Transcription Factor 1
Double Sex and mab-3-related Transcription Factor 1 promoter
Non-obstructive Azoospermia
Texto completo:http://hdl.handle.net/10400.18/3400
País:Portugal
Oai:oai:repositorio.insa.pt:10400.18/3400

Texto Completo

http://hdl.handle.net/10400.18/3400

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