Eugenol derivatives with potential insecticide activity

In the present work, semisynthetic eugenol derivatives were obtained through epoxidation reaction followed by epoxide opening with nucleophiles, such as sodium azide and sodium cyanide. The optimization of the various reactions was performed using different experimental conditions. The main objectiv...

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Bibliographic Details
Main Author: Coelho, José Ricardo Alves (author)
Other Authors: Fernandes, Maria José Gomes (author), Pereira, David M. (author), Castanheira, Elisabete M. S. (author), Fortes, A. Gil (author), Gonçalves, M. Sameiro T. (author)
Format: conferenceObject
Language:eng
Published: 2021
Subjects:
Online Access:http://hdl.handle.net/1822/75234
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/75234
Description
Summary:In the present work, semisynthetic eugenol derivatives were obtained through epoxidation reaction followed by epoxide opening with nucleophiles, such as sodium azide and sodium cyanide. The optimization of the various reactions was performed using different experimental conditions. The main objective behind obtaining these eugenol derivatives was their evaluation as alternative insecticides, thus the biological activity of all compounds was compared to a commercial synthetic insecticide and tested against Sf9 (Spodoptera frugiperda) insect cell line.