HFE Related Hemochromatosis: Uncovering the Inextricable Link between Iron Homeostasis and the Immunological System

The HFE gene (OMIM 235200), most commonly associated with the genetic iron overload disorder Hemochromatosis, was identified by Feder et al. in 1996, as a major histocompatibilty complex (MHC) class I like gene, first designated human leukocyte antigen-H (HLA-H). This discovery was thus accomplished...

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Bibliographic Details
Main Author: Porto, Graça (author)
Other Authors: Cruz, Eugénia (author), Teles, M. (author), de Sousa, Maria (author)
Format: article
Language:eng
Published: 2020
Subjects:
Online Access:http://hdl.handle.net/10400.16/2438
Country:Portugal
Oai:oai:repositorio.chporto.pt:10400.16/2438