HFE Related Hemochromatosis: Uncovering the Inextricable Link between Iron Homeostasis and the Immunological System

The HFE gene (OMIM 235200), most commonly associated with the genetic iron overload disorder Hemochromatosis, was identified by Feder et al. in 1996, as a major histocompatibilty complex (MHC) class I like gene, first designated human leukocyte antigen-H (HLA-H). This discovery was thus accomplished...

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Detalhes bibliográficos
Autor principal: Porto, Graça (author)
Outros Autores: Cruz, Eugénia (author), Teles, M. (author), de Sousa, Maria (author)
Formato: article
Idioma:eng
Publicado em: 2020
Assuntos:
Texto completo:http://hdl.handle.net/10400.16/2438
País:Portugal
Oai:oai:repositorio.chporto.pt:10400.16/2438