Comparison of pathway analysis and constraint-based methods for cell factory design

Background: Computational strain optimisation methods (CSOMs) have been successfully used to exploit genome-scale metabolic models, yielding strategies useful for allowing compound overproduction in metabolic cell factories. Minimal cut sets are particularly interesting since their definition allows...

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Bibliographic Details
Main Author: Vieira, Vítor (author)
Other Authors: Maia, Paulo (author), Rocha, Miguel (author), Rocha, Isabel (author)
Format: article
Language:eng
Published: 2020
Subjects:
Computational strain design
Evolutionary algorithms
Genome-scale metabolic models
Growth-coupled product synthesis
Metabolic pathway analysis
Minimal cut sets
Structural Biology
Biochemistry
Molecular Biology
Computer Science Applications
Applied Mathematics
Online Access:http://hdl.handle.net/10362/95921
Country:Portugal
Oai:oai:run.unl.pt:10362/95921

Internet

http://hdl.handle.net/10362/95921

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