GW274150, a potent and highly selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury

Background. Generation of nitric oxide (NO) by inducible nitric oxide synthase (iNOS) may contribute to renal ischemia/reperfusion (I/R) injury. The aim of this study was to investigate the effects of GW274150, a novel, highly selective, potent and long-acting inhibitor of iNOS activity in rat and m...

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Bibliographic Details
Main Author: Chatterjee, PK (author)
Other Authors: Patel, NSA (author), Sivarajah, A (author), Kvale, EO (author), Dugo, L (author), Cuzzocrea, S (author), Brown, PAJ (author), Stewart, KN (author), Mota-Filipe, H (author), Britti, D (author), Yaqoob, MM (author), Thiemermann, C (author)
Format: article
Language:eng
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10451/21222
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21222