5-(Hydroxyphenyl)-γ-valerolactone-sulfate, a key microbial metabolite of flavan-3-ols, is able to reach the brain

Phenolic compounds have been recognized as promising compounds for the prevention of chronic diseases, including neurodegenerative ones. However, phenolics like flavan-3-ols (F3O) are poorly absorbed along the gastrointestinal tract and structurally rearranged by gut microbiota, yielding smaller and...

ver descrição completa

Detalhes bibliográficos
Autor principal: Angelino, Donato (author)
Outros Autores: Carregosa, Diogo (author), Domenech-Coca, Cristina (author), Savi, Monia (author), Figueira, Inês (author), Brindani, Nicoletta (author), Jang, Saebyeol (author), Lakshman, Sukla (author), Molokin, Aleksey (author), Urban, Joseph F. (author), Davis, Cindy D. (author), Brito, Maria Alexandra (author), Kim, Kwang Sik (author), Brighenti, Furio (author), Curti, Claudio (author), Bladé, Cinta (author), Del Bas, Josep M. (author), Stilli, Donatella (author), Solano-Aguilar, Gloria I. (author), Dos Santos, Claudia Nunes (author), Del Rio, Daniele (author), Mena, Pedro (author)
Formato: article
Idioma:eng
Publicado em: 2019
Assuntos:
Blood brain barrier
Catechin
Flavan-3-ol
Gut
Metabolites
Neurodegenerative disease
Permeability
Polyphenols
Proanthocyanidin
Valerolactone
Food Science
Nutrition and Dietetics
Texto completo:https://doi.org/10.3390/nu11112678
País:Portugal
Oai:oai:run.unl.pt:10362/88419

Texto Completo

https://doi.org/10.3390/nu11112678

Registros relacionados