The multifaceted Foxp3fgfp allele enhances spontaneous and therapeutic immune surveillance of cancer in mice

It is well established that therapeutic impairment of Foxp3+ Treg in mice and humans favors immune rejection of solid tumors. Less explored is the impact Foxp3 allelic variants may have on tumor incidence, progression and therapy. In this work, we tested and demonstrate that the Foxp3fgfp reporter a...

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Bibliographic Details
Main Author: Almeida-Santos, Jose (author)
Other Authors: Bergman, Marie-Louise (author), Jocelyne, Demengeot (author), Correia, Vasco (author), Caramalho, Iris (author), Cabral, Ines (author)
Format: article
Language:eng
Published: 2020
Subjects:
Online Access:http://hdl.handle.net/10400.7/926
Country:Portugal
Oai:oai:arca.igc.gulbenkian.pt:10400.7/926