Autophagy triggered by ursolic acid synergistically enhances 5-fluorouracil induced cell death in HCT15 (MSI p53 mutant) colorectal cancer cells

Colorectal carcinoma (CRC) is a common cause of cancer-related death and tumors with microsatellite instability (MSI) and p53 mutations have been shown to be resistant to chemotherapy with 5-fluorouracil (5-FU). Therefore, it is essential to find compounds that could contribute to treatment efficacy...

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Detalhes bibliográficos
Autor principal: Xavier, Cristina P. R. (author)
Outros Autores: Lima, Cristóvão F. (author), Rohde, Mikkel (author), Wilson, Cristina Pereira (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2011
Texto completo:https://hdl.handle.net/1822/16012
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/16012