Improved synthesis of amino acid and dipeptide chloromethyl esters using bromochloromethane
Peptide chloromethyl esters are important compounds in prodrug synthesis. A simple, mild and efficient method for the synthesis of chloromethyl esters of N-blocked amino acids and dipeptides using exclusively bromochloromethane is reported. These N-blocked amino acid and dipeptide chloromethyl ester...
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| Other Authors: | , , , |
| Format: | article |
| Language: | eng |
| Published: |
2003
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| Subjects: | |
| Online Access: | https://repositorio-aberto.up.pt/handle/10216/82037 |
| Country: | Portugal |
| Oai: | oai:repositorio-aberto.up.pt:10216/82037 |