Sequential ionic and thermogelation of chitosan spherical hydrogels prepared using superhydrophobic surfaces to immobilize cells and drugs

Chitosan is soluble in acidic media, which makes it incompatible for the encapsulation of cells and pH-sensitive molecules. In this work, a mild chitosan-based system with two sequential gelation steps is proposed, where the model drug dexamethasone and L929 cells are immobilized inside hydrogel bea...

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Bibliographic Details
Main Author: Lima, A. C. (author)
Other Authors: Correia, Clara R. (author), Oliveira, Mariana B. (author), Mano, J. F. (author)
Format: article
Language:eng
Published: 2014
Subjects:
Bioencapsulation
Biomaterials
Cell immobilization
Chitosan
Drug delivery
Particles
Superhydrophobic surfaces
Tripolyphosphate
β-glycerophosphate
ß-glycerophosphate
Science & Technology
Online Access:http://hdl.handle.net/1822/27695
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/27695

Internet

http://hdl.handle.net/1822/27695

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