Synthesis of tacrine analogues derived from n-aryl-5-amino-4-cyanopyrazoles

Synthesis of eleven tacrine analogues derived from N-aryl-5-amino-4-cyanopyrazoles, by a Friedländer type reaction, is described. Their structures were confirmed by 1H and 13C NMR spectroscopy, elemental analysis and/or mass spectrometry.

Bibliographic Details
Main Author: Rodrigues, Lígia M. (author)
Other Authors: Francisco, Carla Santana (author), Campos, Ana M. F. Oliveira (author), Salaheldin, Abdellatif M. (author)
Format: article
Language:eng
Published: 2008
Subjects:
Alzheimer’s disease
Friedländer reaction
Aminocyanopyrazole,
Niitrogen heterocycles
Tacrine analogues,
Friedlander reaction
nitrogen heterocycles
tacrine analogs
Science & Technology
Online Access:http://hdl.handle.net/1822/12596
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/12596

Internet

http://hdl.handle.net/1822/12596

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