GDNF modulates HO-1 expression in substantia nigra postnatal cell cultures

Heme oxygenase-1 (HO-1) has been strongly highlighted because of its induction in many cell types by toxic stimuli, including oxidative stress. The intense HO-1 immunostaining in the substantia nigra of Parkinson disease (PD) patients suggests its involvement in the pathogenesis of this neurodegener...

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Bibliographic Details
Main Author: Saavedra, Ana (author)
Other Authors: Baltazar, Graça (author), Carvalho, Caetana M. (author), Duarte, Emília P. (author)
Format: article
Language:eng
Published: 2005
Subjects:
Astrocytes
Dopaminergic neurons
Glial cell line-derived neurotrophic factor
Heme oxygenase-1
Oxidative stress
Parkinson disease
Free radicals
Online Access:http://hdl.handle.net/10316/5358
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/5358

Internet

http://hdl.handle.net/10316/5358

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