Three-dimensional self-assembling nanofiber matrix rejuvenates aged/degenerative human tendon stem/progenitor cells

The poor healing capacity of tendons is known to worsen in the elderly. During tendon aging and degeneration, endogenous human tendon stem/progenitor cells (hTSPCs) experience profound pathological changes. Here, we explored a rejuvenation strategy for hTSPCs derived from aged/degenerated Achilles t...

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Bibliographic Details
Main Author: Yin, Heyong (author)
Other Authors: Strunz, Franziska (author), Yan, Zexing (author), Lu, Jiaju (author), Brochhausen, Christoph (author), Kiderlen, Stefanie (author), Clausen-Schaumann, Hauke (author), Wang, Xiumei (author), Gomes, Manuela E. (author), Alt, Volker (author), Docheva, Denitsa (author)
Format: article
Language:eng
Published: 2020
Subjects:
3D microenvironment
Cell
Cell aging
Hydrogel
Rejuvenation
Stem/progenitor
Stem/progenitor cell
Science & Technology
Online Access:http://hdl.handle.net/1822/64376
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/64376

Internet

http://hdl.handle.net/1822/64376

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