Characterization of widespread proteome aggregation through aging in mammals

Proteome and proteostasis network disruptions accompany proteostasis alterations, leading to accumulation of protein aggregates, characteristic of several age-related diseases. Previous work in Caenorhabditis elegans and zebrafish unveiled asymptomatic protein aggregation (ARPA), characterized by ge...

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Detalhes bibliográficos
Autor principal: Francisco, Stephany (author)
Outros Autores: Nobre, Ana (author), Santa, Cátia (author), Martins, Filipa (author), Camões, Fátima (author), Rebelo, Sandra (author), Manadas, Bruno (author), Santos, Manuel (author), Soares, Ana (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2020
Assuntos:
Proteostasis
Aging
Protein aggregation
Texto completo:http://hdl.handle.net/10773/27855
País:Portugal
Oai:oai:ria.ua.pt:10773/27855

Texto Completo

http://hdl.handle.net/10773/27855

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