Derivation of Brain Capillary-like Endothelial Cells from Human Pluripotent Stem Cell-Derived Endothelial Progenitor Cells

The derivation of human brain capillary endothelial cells is of utmost importance for drug discovery programs focusing on diseases of the central nervous system. Here, we describe a two-step differentiation protocol to derive brain capillary-like endothelial cells from human pluripotent stem cells....

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Bibliographic Details
Main Author: Praça, Catarina (author)
Other Authors: Rosa, Susana C. (author), Sevin, Emmanuel (author), Cecchelli, Romeo (author), Dehouck, Marie-Pierre (author), Ferreira, Lino S. (author)
Format: article
Language:eng
Published: 2019
Subjects:
blood-brain barrier; brain capillary-like endothelial cells; extracellular matrices; induced pluripotent stem cells; in vitro model; soluble factors
Biomarkers
Blood-Brain Barrier
Cells, Cultured
Endothelial Progenitor Cells
Endothelium, Vascular
Extracellular Matrix
Humans
Immunophenotyping
Pluripotent Stem Cells
Cell Differentiation
Online Access:http://hdl.handle.net/10316/92392
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/92392

Internet

http://hdl.handle.net/10316/92392

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