Derivation of Brain Capillary-like Endothelial Cells from Human Pluripotent Stem Cell-Derived Endothelial Progenitor Cells

The derivation of human brain capillary endothelial cells is of utmost importance for drug discovery programs focusing on diseases of the central nervous system. Here, we describe a two-step differentiation protocol to derive brain capillary-like endothelial cells from human pluripotent stem cells....

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Detalhes bibliográficos
Autor principal: Praça, Catarina (author)
Outros Autores: Rosa, Susana C. (author), Sevin, Emmanuel (author), Cecchelli, Romeo (author), Dehouck, Marie-Pierre (author), Ferreira, Lino S. (author)
Formato: article
Idioma:eng
Publicado em: 2019
Assuntos:
blood-brain barrier; brain capillary-like endothelial cells; extracellular matrices; induced pluripotent stem cells; in vitro model; soluble factors
Biomarkers
Blood-Brain Barrier
Cells, Cultured
Endothelial Progenitor Cells
Endothelium, Vascular
Extracellular Matrix
Humans
Immunophenotyping
Pluripotent Stem Cells
Cell Differentiation
Texto completo:http://hdl.handle.net/10316/92392
País:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/92392

Texto Completo

http://hdl.handle.net/10316/92392

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