CYP2C19*2 and prognosis after an acute coronary syndrome: Insights from a Portuguese center

BACKGROUND: Clopidogrel requires oxidation dependent on the cytochrome P450 enzyme 2C19 (CYP2C19) to form its active metabolite. The importance of loss-of-function alleles (particularly CYP2C19*2, 681G>A) in poor platelet response to clopidogrel is well recognized. OBJECTIVE: To investigate the p...

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Detalhes bibliográficos
Autor principal: Teixeira, R (author)
Outros Autores: Monteiro, P (author), Marques, G (author), Pego, J (author), Lourenço, M (author), Tavares, C (author), Reboredo, A (author), Monteiro, S (author), Gonçalves, F (author), Ferreira, MJ (author), Freitas, M (author), Ribeiro, G (author), Providência, LA (author)
Formato: article
Idioma:eng
Publicado em: 2012
Assuntos:
Síndrome Coronária Aguda
Prognóstico
Texto completo:http://hdl.handle.net/10400.4/1344
País:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/1344

Texto Completo

http://hdl.handle.net/10400.4/1344

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