Co-silencing of human Bub3 and dynein highlights an antagonistic relationship in regulating kinetochore-microtubule attachments

We previously reported that the spindle assembly checkpoint protein Bub3 is involved in regulating kinetochore-microtubule (KT-MT) attachments. Also, Bub3 was reported to interact with the microtubule motor protein dynein. Here we examined how this interaction contributes to KT-MT attachments. Deple...

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Bibliographic Details
Main Author: Silva, Patricia M. A. (author)
Other Authors: Tavares, Alvaro A. (author), Bousbaa, Hassan (author)
Format: article
Language:eng
Published: 2018
Subjects:
Spindle-assembly checkpoint
Cytoplasmic dynein
Mitotic checkpoint
Mitosis
Congression
Protein
Cells
Online Access:http://hdl.handle.net/10400.1/11770
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/11770

Internet

http://hdl.handle.net/10400.1/11770

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