Cannabinoid modulation of limbic forebrain noradrenergic circuitry

Both the endocannabinoid and noradrenergic systems have been implicated in neuropsychiatric disorders. Importantly, low levels of norepinephrine are seen in patients with depression, and antagonism of the cannabinoid receptor type 1 (CB1R) is able to induce depressive symptoms in rodents and humans....

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Detalhes bibliográficos
Autor principal: Carvalho, Ana Raquel Franky Gomes (author)
Outros Autores: Mackie, Kenneth (author), Van Bockstaele, Elisabeth J. (author)
Formato: article
Idioma:eng
Publicado em: 2010
Assuntos:
Animals
Benzoxazines
Calcium channel blockers
Cannabinoid receptor modulators
Cannabinoids
Humans
Male
Morpholines
Naphthalenes
Neurons
Norepinephrine
Rats
Rats, Sprague-Dawley
Receptor, Cannabinoid, CB1
Receptors, Adrenergic, alpha-2
Receptors, Adrenergic, beta-1
Synapses
Limbic system
Neural pathways
Prosencephalon
adrenergic receptor
cannabinoid receptor type 1
nucleus accumbens
nucleus of the solitary tract
Sprague-Dawley
Science & Technology
Texto completo:http://hdl.handle.net/1822/67527
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/67527

Texto Completo

http://hdl.handle.net/1822/67527

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