Methyl-cyclopentadienyl ruthenium compounds with 2,2 '-bipyridine derivatives display strong anticancer activity and multidrug resistance potential

New ruthenium methyl-cyclopentadienyl compounds bearing bipyridine derivatives with the general formula [Ru(eta(5)-MeCp)(PPh3)(4,4'-R-2,2'-bpy)](+) (Ru1, R = H; Ru2, R = CH3; and Ru3, R = CH2OH) have been synthesized and characterized by spectroscopic and analytical techniques. Ru1 crystal...

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Bibliographic Details
Main Author: Côrte-Real, Leonor (author)
Other Authors: Gonçalves Teixeira, Ricardo (author), Girio, Patrícia (author), Comsa, Elisabeta (author), MORENO, Alexis (author), Nasr, Rachad (author), Baubichon-Cortay, Helene (author), Avecilla, Fernando (author), Marques, Fernanda (author), Robalo, Maria Paula (author), Mendes, Paulo (author), Prates Ramalho, João P. (author), Garcia (author), Falson, Pierre (author), Valente, Andreia (author)
Format: article
Language:eng
Published: 2018
Subjects:
Spectroscopic
Multidrug resistance
Cytotoxic profile
Online Access:http://hdl.handle.net/10400.21/9123
Country:Portugal
Oai:oai:repositorio.ipl.pt:10400.21/9123

Internet

http://hdl.handle.net/10400.21/9123

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