The Na+ -Coupled Glucose Transporter SGLT2 Interacts with its Accessory Unit MAP17 in Vitro and Their expressions overlap in the renal proximal tubule

Na+ -glucose cotransporter 2 is the renal Na+ -coupled glucose transporter responsible for the tubular glucose reabsorption, while MAP17 was recently identified as its accessory unit. Mutations in either of the proteins' coding genes, SLC5A2 and PDZK1IP1, lead to urinary glucose excretion. To i...

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Detalhes bibliográficos
Autor principal: Calado, J (author)
Outros Autores: Santos, AR (author), Aires, I (author), Lebre, F (author), Nolasco, F (author), Rueff, J (author), Ramalho, J (author)
Formato: other
Idioma:eng
Publicado em: 2019
Assuntos:
Biological Transport
Epithelium
Glucose
HEK293 Cells
Humans
Kidney
Kidney Tubules, Proximal
Membrane Proteins
Protein Binding
RNA Interference
Sodium
Sodium-Glucose Transporter 2
HCC NEF
Texto completo:http://hdl.handle.net/10400.17/3387
País:Portugal
Oai:oai:repositorio.chlc.min-saude.pt:10400.17/3387

Texto Completo

http://hdl.handle.net/10400.17/3387

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