Proteomic analysis of the action of the Mycobacterium ulcerans toxin mycolactone: targeting host cells cytoskeleton and collagen

Buruli ulcer (BU) is a neglected tropical disease caused by Mycobacterium ulcerans. The tissue damage characteristic of BU lesions is known to be driven by the secretion of the potent lipidic exotoxin mycolactone. However, the molecular action of mycolactone on host cell biology mediating cytopathog...

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Bibliographic Details
Main Author: Gama, José B. (author)
Other Authors: Ohlmeier, S. (author), Martins, Teresa G. (author), Fraga, Alexandra G. (author), Marques, Belém Sampaio (author), Carvalho, M. Alice (author), Proença, M. Fernanda R. P. (author), Silva, Manuel T. (author), Pedrosa, Jorge (author), Ludovico, Paula (author)
Format: article
Language:eng
Published: 2014
Subjects:
Science & Technology
Online Access:http://hdl.handle.net/1822/32476
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/32476

Internet

http://hdl.handle.net/1822/32476

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