Proteomic analysis of the action of the Mycobacterium ulcerans toxin mycolactone: targeting host cells cytoskeleton and collagen

Buruli ulcer (BU) is a neglected tropical disease caused by Mycobacterium ulcerans. The tissue damage characteristic of BU lesions is known to be driven by the secretion of the potent lipidic exotoxin mycolactone. However, the molecular action of mycolactone on host cell biology mediating cytopathog...

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Detalhes bibliográficos
Autor principal: Gama, José B. (author)
Outros Autores: Ohlmeier, S. (author), Martins, Teresa G. (author), Fraga, Alexandra G. (author), Marques, Belém Sampaio (author), Carvalho, M. Alice (author), Proença, M. Fernanda R. P. (author), Silva, Manuel T. (author), Pedrosa, Jorge (author), Ludovico, Paula (author)
Formato: article
Idioma:eng
Publicado em: 2014
Assuntos:
Texto completo:http://hdl.handle.net/1822/32476
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/32476