Evaluation of the antitumoral effect mediated by IL-12 and HSV-tk genes when delivered by a novel lipid-based system

In the present work, we used a novel albumin-associated lipoplex formulation, containing the cationic lipid 1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (EPOPC) and cholesterol (Chol), to evaluate the antitumoral efficacy of two gene therapy strategies: immuno-gene therapy, mediated by IL-1...

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Detalhes bibliográficos
Autor principal: Faneca, H. (author)
Outros Autores: Cabrita, A. S. (author), Simões, S. (author), Lima, M. C. Pedroso de (author)
Formato: article
Idioma:eng
Publicado em: 2007
Assuntos:
Texto completo:http://hdl.handle.net/10316/4720
País:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/4720