Amino acids as selective sulfonamide acylating agents

Acylation of antimalarial and bacteriostatic sulfonamides with N-protected amino acids and peptides was carried out using standard peptide coupling methods. These acylation reactions are regioselective for the N-4 nitrogen atom of diazine-containing sulfonamides. In contrast, only N-1 coupling was f...

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Detalhes bibliográficos
Autor principal: Gomes, P (author)
Outros Autores: Gomes, JRB (author), Rodrigues, M (author), Moreira, R (author)
Formato: article
Idioma:eng
Publicado em: 2003
Assuntos:
Texto completo:https://hdl.handle.net/10216/82048
País:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/82048