Synthesis of novel pyrazolo[3,4-b]quinoline-bisphosphonic acids and an unexpected intramolecular cyclization and phosphonylation reaction

ABSTRACT: Novel pyrazolo[3,4-b]quinoline alpha-ketophosphonic and hydroxymethylenebisphosphonic acid compounds were synthesized using different methodologies, starting from 2-chloro-3-formylquinoline 1. New phosphonic acid compounds were obtained as N-1 derivatives with a side chain with 1 or 3 (n =...

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Bibliographic Details
Main Author: Teixeira, Fatima (author)
Other Authors: Lucas, Carla (author), Curto, Maria João Marcelo (author), Andre, Vania (author), Duarte, M. Teresa (author), Teixeira, António P. S. (author)
Format: article
Language:eng
Published: 2021
Subjects:
Bisphosphonates
X-ray diffraction
Indazole
Pyrazolo[3,4-b]pyridine
Pyrazolo[3,4-b]quinoline
Online Access:http://hdl.handle.net/10400.9/3678
Country:Portugal
Oai:oai:repositorio.lneg.pt:10400.9/3678

Internet

http://hdl.handle.net/10400.9/3678

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