Bioengineered hierarchical bonelike compartmentalized microconstructs using nanogrooved microdiscs

Fabrication of vascularized large-scale constructs for regenerative medicine remains elusive since most strategies rely solely on cell self-organization or overly control cell positioning, failing to address nutrient diffusion limitations. We propose a modular and hierarchical tissue-engineering str...

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Bibliographic Details
Main Author: Bjørge, Isabel M. (author)
Other Authors: Sousa, Bárbara M. de (author), Patrício, Sónia G. (author), Silva, Ana Sofia (author), Nogueira, Liebert P. (author), Santos, Lúcia F. (author), Vieira, Sandra I. (author), Haugen, Håvard J. (author), Correia, Clara R. (author), Mano, João F (author)
Format: article
Language:eng
Published: 2023
Subjects:
Biophysical cues
Compartmentalization
Liquefied-core capsules
Nanogrooved microdiscs
Bottom-up tissue engineering
Cell self-assembly
Osteogenesis
Prevascularization
Online Access:http://hdl.handle.net/10773/34587
Country:Portugal
Oai:oai:ria.ua.pt:10773/34587

Internet

http://hdl.handle.net/10773/34587

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