Fabrication of a 3D combinatorial fibrous-porous scaffold for neural tissue engineering applications

The ability of tissue engineered scaffolds to modulate the response of neural stem cells (e.g. adhesion, proliferation and differentiation) is boosting the unlocking of advanced therapeutic strategies capable of attenuating the effects of traumatic pathologies like spinal cord injury [1]. From the w...

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Bibliographic Details
Main Author: Girão, André F. (author)
Other Authors: Sousa, Joana (author), Domínguez-Bajo, Ana (author), González-Mayorga, Ankor (author), Completo, António (author), Serrano, María Concepción (author), Marques, Paula A. A. P. (author)
Format: conferenceObject
Language:eng
Published: 2020
Subjects:
Online Access:http://hdl.handle.net/10773/27991
Country:Portugal
Oai:oai:ria.ua.pt:10773/27991
Description
Summary:The ability of tissue engineered scaffolds to modulate the response of neural stem cells (e.g. adhesion, proliferation and differentiation) is boosting the unlocking of advanced therapeutic strategies capable of attenuating the effects of traumatic pathologies like spinal cord injury [1]. From the wide range of reported scaffolding concepts, it has been consistently demonstrated that nanofibrous networks and graphene-based porous systems are proficient for guiding neurite outgrowth and inducing specific differentiation patterns, respectively [2].