Peptidomimetic and Organometallic Derivatives of Primaquine Active against Leishmania infantum

The current treatment of visceral leishmaniasis is made difficult by the low efficacy, elevated costs, low bioavailability, and high toxicity of many of the available drugs. Primaquine, an antimalarial 8-aminoquinoline, displays activity against Leishmania spp., and several of its derivatives have b...

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Detalhes bibliográficos
Autor principal: Silvia Vale Costa (author)
Outros Autores: Nuno Vale (author), Joana Matos (author), Ana Tomas (author), Rui Moreira (author), Paula Gomes (author), Maria Salome Gomes (author)
Formato: article
Idioma:eng
Publicado em: 2012
Assuntos:
Texto completo:https://hdl.handle.net/10216/82050
País:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/82050