Expression and function of the insulin receptor in normal and osteoarthritic human chondrocytes: modulation of anabolic gene expression, glucose transport and GLUT-1 content by insulin

OBJECTIVE: Chondrocytes respond to insulin, but the presence and role of the specific high affinity insulin receptor (InsR) has never been demonstrated. This study determined whether human chondrocytes express the InsR and compared its abundance and function in normal and osteoarthritis (OA) human c...

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Bibliographic Details
Main Author: Rosa, SC (author)
Other Authors: Rufino, AT (author), Judas, F (author), Tenreiro, C (author), Lopes, MC (author), Mendes, AF (author)
Format: article
Language:eng
Published: 2011
Subjects:
Condrócitos
Osteoartrite
Online Access:http://hdl.handle.net/10400.4/1192
Country:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/1192

Internet

http://hdl.handle.net/10400.4/1192

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