Expression and function of the insulin receptor in normal and osteoarthritic human chondrocytes: modulation of anabolic gene expression, glucose transport and GLUT-1 content by insulin

OBJECTIVE: Chondrocytes respond to insulin, but the presence and role of the specific high affinity insulin receptor (InsR) has never been demonstrated. This study determined whether human chondrocytes express the InsR and compared its abundance and function in normal and osteoarthritis (OA) human c...

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Detalhes bibliográficos
Autor principal: Rosa, SC (author)
Outros Autores: Rufino, AT (author), Judas, F (author), Tenreiro, C (author), Lopes, MC (author), Mendes, AF (author)
Formato: article
Idioma:eng
Publicado em: 2011
Assuntos:
Texto completo:http://hdl.handle.net/10400.4/1192
País:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/1192