Novel mechanisms causing Familial Hypercholesterolaemia: Functional characterization of variants in the regulatory regions of PCSK9 and LDLR genes

AiM: To define the 5’UTR and promoter regions of the PCSK9 gene, as well as, to perform an in vitro characterization of variants in LDLR and PCSK9 genes in the regulatory regions mentioned above. This project will also contribute to an accurate identification of FH patients allowing for a better pat...

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Bibliographic Details
Main Author: Alves, Ana Catarina (author)
Other Authors: Menezes, Juliane (author)
Format: conferenceObject
Language:eng
Published: 2021
Subjects:
Familial Hypercholesterolaemia
Functional Characterization
LDLR Gene
PCSK9 Gene
Doenças Cardio e Cérebro-vasculares
Online Access:http://hdl.handle.net/10400.18/7713
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/7713

Internet

http://hdl.handle.net/10400.18/7713

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