Skipping EXON-v6 from CD44V6-containing isoforms influences chemotherapy response and self-renewal capacity of gastric cancer cells

De novo expressed CD44 isoforms containing exon-v6 are frequently associated with gastric cancer (GC) aggressiveness, and may predict chemotherapy response in vitro. Whether exon-v6 itself is responsible for conferring these properties to CD44v6-containing isoforms remains to be elucidated. CRISPR/C...

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Bibliographic Details
Main Author: Lobo, S (author)
Other Authors: Pereira, C (author), Oliveira, C (author), Almeida, GM (author)
Format: article
Language:eng
Published: 2020
Subjects:
Cell survival
Chemoresistance
CRISPR/Cas9
Exon skipping
Morpholinos
Stomach neoplasms
Online Access:https://hdl.handle.net/10216/143543
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/143543

Internet

https://hdl.handle.net/10216/143543

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