Functionalized gold nanoparticles improve afatinib delivery into cancer cells

Objectives: A drug delivery system based on colloidal pegylated gold nanoparticles (PEGAuNPs) conjugated with the tyrosine kinase inhibitor afatinib was designed and tested for enhancing the drug activity against pancreatic and NSCLC cells. Methods: PEGAuNPs were synthesized and characterized physic...

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Bibliographic Details
Main Author: Sílvia Castro Coelho (author)
Other Authors: Gabriela M. Almeida (author), Maria do Carmo Pereira (author), Filipe Santos-Silva (author), Manuel A. N. Coelho (author)
Format: article
Language:eng
Published: 2016
Subjects:
Nanotecnologia
Nano-technology
Online Access:https://hdl.handle.net/10216/103243
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/103243

Internet

https://hdl.handle.net/10216/103243

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