Functionalized gold nanoparticles improve afatinib delivery into cancer cells

Objectives: A drug delivery system based on colloidal pegylated gold nanoparticles (PEGAuNPs) conjugated with the tyrosine kinase inhibitor afatinib was designed and tested for enhancing the drug activity against pancreatic and NSCLC cells. Methods: PEGAuNPs were synthesized and characterized physic...

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Detalhes bibliográficos
Autor principal: Sílvia Castro Coelho (author)
Outros Autores: Gabriela M. Almeida (author), Maria do Carmo Pereira (author), Filipe Santos-Silva (author), Manuel A. N. Coelho (author)
Formato: article
Idioma:eng
Publicado em: 2016
Assuntos:
Nanotecnologia
Nano-technology
Texto completo:https://hdl.handle.net/10216/103243
País:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/103243

Texto Completo

https://hdl.handle.net/10216/103243

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