Chromosomes. CENP-C reshapes and stabilizes CENP-A nucleosomes at the centromere

Inheritance of each chromosome depends upon its centromere. A histone H3 variant, centromere protein A (CENP-A), is essential for epigenetically marking centromere location. We find that CENP-A is quantitatively retained at the centromere upon which it is initially assembled. CENP-C binds to CENP-A...

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Bibliographic Details
Main Author: Falk, S. J. (author)
Other Authors: Guo, L. Y. (author), Sekulic, N. (author), Smoak, E. M. (author), Mani, T. (author), Logsdon, G. A. (author), Gupta, K. (author), Jansen, L. E. T. (author), Van Duyne, G. D. (author), Vinogradov, S. A. (author), Lampson, M. A. (author), Black, B. E. (author)
Format: article
Language:eng
Published: 2016
Subjects:
Autoantigens
Centromere
Chromosomal Proteins, Non-Histone
DNA
Epigenesis, Genetic
Fluorescence Resonance Energy Transfer
Gene Knockdown Techniques
Humans
Nucleosomes
Protein Structure, Secondary
Online Access:http://hdl.handle.net/10400.7/627
Country:Portugal
Oai:oai:arca.igc.gulbenkian.pt:10400.7/627

Internet

http://hdl.handle.net/10400.7/627

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