Artemisinin resistance in rodent malaria - Mutation in the AP2 adaptor μ-chain suggests involvement of endocytosis and membrane protein trafficking

Background: The control of malaria, caused by Plasmodium falciparum, is hampered by the relentless evolution of drug resistance. Because artemisinin derivatives are now used in the most effective anti-malarial therapy, resistance to artemisinin would be catastrophic. Indeed, studies suggest that art...

ver descrição completa

Detalhes bibliográficos
Autor principal: Henriques, Gisela (author)
Outros Autores: Martinelli, Axel (author), Rodrigues, Louise (author), Modrzynska, Katarzyna (author), Fawcett, Richard (author), Houston, Douglas R. (author), Borges, Sofia T. (author), D'Alessandro, Umberto (author), Tinto, Halidou (author), Karema, Corine (author), Hunt, Paul (author), Cravo, Pedro (author)
Formato: article
Idioma:eng
Publicado em: 2021
Assuntos:
Artemisinin
Drug resistance
Endocytic machinery
Genomics
Malaria
Mutation
Plasmodium chabaudi
Parasitology
Infectious Diseases
Genetics
SDG 3 - Good Health and Well-being
Texto completo:http://hdl.handle.net/10362/117026
País:Portugal
Oai:oai:run.unl.pt:10362/117026

Texto Completo

http://hdl.handle.net/10362/117026

Registos relacionados