Combined inhibition of FOSL-1 and YAP Using siRNA-lipoplexes reduces the growth of pancreatic tumor

Pancreatic cancer evades most of the current therapies and there is an urgent need for new treatments that could efficiently eliminate this aggressive tumor, such as the blocking of routes driving cell proliferation. In this work, we propose the use of small interfering RNA (siRNA) to inhibit the co...

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Bibliographic Details
Main Author: Diego-González, Lara (author)
Other Authors: Fernández-Carrera, Andrea (author), Igea, Ana (author), Martínez-Pérez, Amparo (author), Real Oliveira, M. Elisabete C. D. (author), Gomes, Andreia C (author), Guerra, Carmen (author), Barbacid, Mariano (author), González-Fernández, África (author), Simón-Vázquez, Rosana (author)
Format: article
Language:eng
Published: 2022
Subjects:
pancreatic ductal adenocarcinoma
nanomedicine
liposomes
gene silencing
KRAS
Hippo pathway
Ciências Médicas::Medicina Básica
Science & Technology
Online Access:https://hdl.handle.net/1822/80262
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/80262

Internet

https://hdl.handle.net/1822/80262

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