Combined inhibition of FOSL-1 and YAP Using siRNA-lipoplexes reduces the growth of pancreatic tumor

Pancreatic cancer evades most of the current therapies and there is an urgent need for new treatments that could efficiently eliminate this aggressive tumor, such as the blocking of routes driving cell proliferation. In this work, we propose the use of small interfering RNA (siRNA) to inhibit the co...

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Detalhes bibliográficos
Autor principal: Diego-González, Lara (author)
Outros Autores: Fernández-Carrera, Andrea (author), Igea, Ana (author), Martínez-Pérez, Amparo (author), Real Oliveira, M. Elisabete C. D. (author), Gomes, Andreia C (author), Guerra, Carmen (author), Barbacid, Mariano (author), González-Fernández, África (author), Simón-Vázquez, Rosana (author)
Formato: article
Idioma:eng
Publicado em: 2022
Assuntos:
pancreatic ductal adenocarcinoma
nanomedicine
liposomes
gene silencing
KRAS
Hippo pathway
Ciências Médicas::Medicina Básica
Science & Technology
Texto completo:https://hdl.handle.net/1822/80262
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/80262

Texto Completo

https://hdl.handle.net/1822/80262

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