Translational switch during integrated stress response: the examples of p53 and UPF1

The scanning model for eukaryotic mRNA translation initiation states that the small ribosomal subunit, along with initiation factors, binds to the cap structure at the 5’ end of the mRNA and scans the 5’ untranslated region (5’UTR) until an initiation codon is found. However, when cells are exposed...

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Detalhes bibliográficos
Autor principal: Lacerda, Rafaela (author)
Outros Autores: Pereira, Bruna (author), Menezes, Juliane (author), Ramos, Ana (author), Neves, Ana Rita (author), Candeias, Marco M (author), Romão, Luísa (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2020
Assuntos:
mRNA Translation
p53
UPF1
Doenças Genéticas
Genómica Funcional e Estrutural
Texto completo:http://hdl.handle.net/10400.18/7468
País:Portugal
Oai:oai:repositorio.insa.pt:10400.18/7468

Texto Completo

http://hdl.handle.net/10400.18/7468

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