Aluminium-induced changes of fusion pore properties attenuate prolactin secretion in rat pituitary lactotrophs

Hormone secretion is mediated by Ca(2+)-regulated exocytosis. The key step of this process consists of the merger of the vesicle and the plasma membranes, leading to the formation of a fusion pore. This is an aqueous channel through which molecules stored in the vesicle lumen exit into the extracell...

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Bibliographic Details
Main Author: Calejo, A. I. (author)
Other Authors: Jorgačevski, J. (author), Silva, V. S. (author), Stenovec, M. (author), Kreft, M. (author), Gonçalves, P. P. (author), Zorec, R. (author)
Format: article
Language:eng
Published: 2019
Subjects:
Online Access:http://hdl.handle.net/10773/26308
Country:Portugal
Oai:oai:ria.ua.pt:10773/26308