The era of RNA interference medicines: the clinical landscape of synthetic gene silencing drugs
Therapeutic oligonucleotides, such as small interfering RNAs (siRNAs), provide a simple and effective tool to modulate the expression of any gene. siRNAs harness the RNA interference (RNAi) pathway to degrade disease-associated messenger RNAs (mRNAs). The inherent sequence specificity and potency of...
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| Formato: | article |
| Idioma: | por |
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2022
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| Texto completo: | https://doi.org/10.25758/set.2227 |
| País: | Portugal |
| Oai: | oai:journals.ipl.pt:article/536 |