N-Heterocyclic Carbenes Derived from Guanosine

Palladium(II) and platinum(II) complexes bearing N-heterocyclic carbenes derived from guanosine are synthesized via oxidative addition, followed by protonation in the presence of acid. Cytotoxicity of the compounds is evaluated in several cell lines. Compounds 2a, 2b, and 3a are selective for gliobl...

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Detalhes bibliográficos
Autor principal: Leitão, Maria Inês P.S. (author)
Outros Autores: Herrera, Federico (author), Petronilho, Ana (author)
Formato: article
Idioma:eng
Publicado em: 2019
Assuntos:
Texto completo:https://doi.org/10.1021/acsomega.8b02387
País:Portugal
Oai:oai:run.unl.pt:10362/68110