Potential impact of viral load and genetic makeup of HIV type 1 on mother-to-child transmission: characterization of env-C2V3C3 and nef sequences

HIV-1 mother-to-child transmission (MTCT) was evaluated in terms of the molecular characterization of the env and nef genomic regions and quantification of maternal RNA viral loads. Assignment of viral subtype was achieved by direct sequencing of PCR 1172 products amplified from proviral DNA in 45 H...

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Bibliographic Details
Main Author: Pádua, E. (author)
Other Authors: Parreira, R. (author), Tendeiro, R. (author), Nunes, Baltazar (author), Castela, J. (author), Soares, I. (author), Mouzinho, A. (author), Reis, E. (author), Paixão, M.T. (author)
Format: article
Language:eng
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/10400.18/1560
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/1560