Application of 2OMethylRNA antisense oligomer to control Candida albicans EFG1 virulence determinant

Antisense oligomers and their analogues have been successfully utilized to silence gene expression for the treatment of many human diseases; however the control of yeast´s virulence determinants has never been exploited before. In this sense, this work is based on the key hypothesis that if a pathog...

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Bibliographic Details
Main Author: Araújo, Daniela (author)
Other Authors: Azevedo, N. (author), Barbosa, Ana (author), Almeida, Carina (author), Rodrigues, M. Elisa (author), Henriques, Mariana (author), Silva, Sónia Carina (author)
Format: article
Language:eng
Published: 2019
Subjects:
Candidiasis
Filamentation
Nucleic Acid Mimics
2-MethylRNA modification
2′-OMethylRNA modification
Science & Technology
Online Access:http://hdl.handle.net/1822/61935
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/61935

Internet

http://hdl.handle.net/1822/61935

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