Application of 2OMethylRNA antisense oligomer to control Candida albicans EFG1 virulence determinant

Antisense oligomers and their analogues have been successfully utilized to silence gene expression for the treatment of many human diseases; however the control of yeast´s virulence determinants has never been exploited before. In this sense, this work is based on the key hypothesis that if a pathog...

ver descrição completa

Detalhes bibliográficos
Autor principal: Araújo, Daniela (author)
Outros Autores: Azevedo, N. (author), Barbosa, Ana (author), Almeida, Carina (author), Rodrigues, M. Elisa (author), Henriques, Mariana (author), Silva, Sónia Carina (author)
Formato: article
Idioma:eng
Publicado em: 2019
Assuntos:
Candidiasis
Filamentation
Nucleic Acid Mimics
2-MethylRNA modification
2′-OMethylRNA modification
Science & Technology
Texto completo:http://hdl.handle.net/1822/61935
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/61935

Texto Completo

http://hdl.handle.net/1822/61935

Registros relacionados