Enhanced Cellular Uptake and Photodynamic Effect with Amphiphilic Fluorinated Porphyrins: The Role of Sulfoester Groups and the Nature of Reactive Oxygen Species

A class of amphiphilic photosensitizers for photodynamic therapy (PDT) was developed. Sulfonate esters of modified porphyrins bearing-F substituents in the ortho positions of the phenyl rings have adequate properties for PDT, including absorption in the red, increased cellular uptake, favorable intr...

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Detalhes bibliográficos
Autor principal: Pucelik, Barbara (author)
Outros Autores: Sułek, Adam (author), Drozd, Agnieszka (author), Stochel, Grażyna (author), Pereira, Marietta M. (author), Pinto, Sara Martinho Almeida (author), Moreira, Luís Guilherme da Silva Arnaut (author), Dąbrowski, Janusz M. (author)
Formato: article
Idioma:eng
Publicado em: 2020
Assuntos:
Anticancer activity
Photodynamic therapy
Photosensitizers
Porphyrins
Reactive oxygen species
Singlet oxygen
Texto completo:http://hdl.handle.net/10316/90791
País:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/90791

Texto Completo

http://hdl.handle.net/10316/90791

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