Enhanced Cellular Uptake and Photodynamic Effect with Amphiphilic Fluorinated Porphyrins: The Role of Sulfoester Groups and the Nature of Reactive Oxygen Species

A class of amphiphilic photosensitizers for photodynamic therapy (PDT) was developed. Sulfonate esters of modified porphyrins bearing-F substituents in the ortho positions of the phenyl rings have adequate properties for PDT, including absorption in the red, increased cellular uptake, favorable intr...

Full description

Bibliographic Details
Main Author: Pucelik, Barbara (author)
Other Authors: Sułek, Adam (author), Drozd, Agnieszka (author), Stochel, Grażyna (author), Pereira, Marietta M. (author), Pinto, Sara Martinho Almeida (author), Moreira, Luís Guilherme da Silva Arnaut (author), Dąbrowski, Janusz M. (author)
Format: article
Language:eng
Published: 2020
Subjects:
Anticancer activity
Photodynamic therapy
Photosensitizers
Porphyrins
Reactive oxygen species
Singlet oxygen
Online Access:http://hdl.handle.net/10316/90791
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/90791

Internet

http://hdl.handle.net/10316/90791

Similar Items